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Dimension EXL 200 Integrated Chemistry System

Dimension EXL 200 Integrated Chemistry System

Brand: Seimens


The Dimension® EXL™ 200 Integrated Chemistry System with patented LOCI® Advanced Chemiluminescent Technology and automated productivity-enhancing features for both the low-volume laboratory and the STAT laboratory.

Product Details

LOCI technology inside
  • Trusted results in a flash
  • Homogeneous chemiluminescent technology
  • Fast and accurate
  • Excellent precision
  • High sensitivity
  • Short reaction times, no washing or separation steps
  • Excellent STAT testing capability
  • Low sample volume required
True integration
  • Integration of chemistry and immunoassay with a comprehensive menu
  • One sample area
  • Common reagent area
  • Common reagent packaging
Trusted, proven technologies
  • LOCI® advanced chemiluminescence
  • Heterogeneous Module
  • Photometry
  • QuikLYTE® IMT
  • User-defined serum index (HIL) testing
  • Automation capabilities
Workflow efficiency
  • Process any test, any time, any shift
  • Plasma qualified assays
  • Fully automated onboard pretreatment (when required)
Fewer manual tasks
  • Automated calibration and control procedures
  • Infrequent calibration
  • Paperless, electronic data storage
  • Proactive STAT, sample, supply, QC and calibration alerts
  • No manual reagent preparation
  • No manual sample pretreatment
  • No limit or dedicated STAT positions required
System Description Random-access clinical chemistry and immunoassay system with LOCI®  chemiluminescence technology
Test Throughput Performs up to 440 photometric chemistry tests per hour and 187 IMT tests per hour on serum, plasma, urine, and cerebrospinal fluid; can perform up to 167 heterogeneous immunoassay tests per hour
Time to First Result IMT (NA, K, CL): 1.5 min; Electrolytes (IMT + ECO2): 2.9 min; BMP-7  Electrolytes, GLU, BUN, CREA) 4.0 min; CMP-6 (ALB, DBIL, TBIL, AST, ALT, ALP): 9.3 min; TNI: 11 min; HCG: 15.5 min
Assay Capacity Onboard 47 including 3 IMT
Disease-state Assay Groups Anemia, Autoimmune/Rheumatoid, Bone Metabolism, Cardiovascular, Diabetes, Drugs of Abuse/Toxicology, Hepatic Diseases, Immunosuppressive Drugs/TDM, Inflammation, Nephropathies, Nutritional Assessment, Pancreatic Disease, Oncology, Reproductive Endocrinology, Thyroid
Sample Handling
Sample Tubes 5 mL, 7 mL, 10 mL tubes; 1.5 mL sample cups; 1.0 mL small sample containers and pediatric tubes
Sample Wheel 60 sample positions in six 10-tube segments; positive sample identification
STAT Handling Not dedicated; STAT samples are processed with priority
Sample Integrity Check Qualitative check for hemolysis, lipemia, and icterus; clot detection, flagging, and management; short-sample detection, flagging, and management
Auto-Repeat Automatic repeat testing from the original sample
Sample Volume Per Test 2–60 μL
Sample Dilution Automatic dilution: 1:1.5 up to 1:200
Auto-Reflex Testing Automatic reflex testing based on results of first test
Primary Sample Probe Liquid-level sensing, clot detection, short-sample detection
Sample Carryover Prevention Automated wash
Sample Throughput Up to 200 tubes per hour as part of the VersaCell® X3 Solution – Dimension®Suite; faster on automation
Bar Codes
Sample Bar Codes Code 39; Code 128; Codabar (USS); Interleaved 2 of 5 w and w/o check digit, 12 digits maximum
Reaction Area
Reaction Cuvettes Onboard capacity of 12,000 formed cuvettes
Reaction Bath Air; incubation temperature 37°C
Path Length 0.5 cm ±0.0125 cm
Photometer The filter wheel holds optical filters for wavelengths of 293, 340, 383, 405, 452, 510, 540, 577, 600, 680, and 700 nm
Light Source Standard tungsten halogen lamp, operation at 6.5A (6.8v)
Reaction Times 1, 3, 4, 5, 10, 15, 21, and 32 minutes
Automatic Correction Serum blank, cell blank, reagent blank, measurement point change, autodilution
Assay Technologies LOCI, heterogeneous immunoassay, PETINIA and ACMIA, photometry, potentiometry (ISE), turbidimetric, and Emit®
Assay Result Calculations Endpoint, rate, multipoint
Reagent Handling
Reagent Tray 44 positions, refrigerated between 2–8°C (36–47°F)
Reagent Capacity Onboard 44 Flex® Reagent Cartridges plus 3 electrolytes via the QuikLYTE® IMT
Dispensing System 2 probes with liquid-level sensing
Reagent Cartridges Flex Reagent Cartridges, bar coded, 15 to 360 tests/Flex
Average Total Reaction Volume 350–500 μL per test
Reagent Integrity Control Bar-code reagent identification; automatic inventory tracking and flagging; calibration and control validity tracking and flagging; reagent onboard tracking of tests remaining, lot number, onboard stability, and expiration date
Onboard Stability Depending on assay, up to 42 days
Test Capacity Onboard 25,200 tests average; 33,300 tests maximum
Open System Capability
Channels 110 assay channels; includes 10 channels for user-defined applications
IMT Indirect simultaneous measurement of Na+, K+, Cl-
Sample Volume 40 μL for all three tests
Priming Automatic priming cycle, no user calibration, automatic urine dilution 1:10
Expected Use 1000 samples or 5 days, whichever comes first
Validated Calibration Interval Up to 90 days, tracked by software, with 500 most recent calibration logs stored electronically if a system restore is required (starting with software version 10.1)
Auto-Calibration Assay-specific time interval or with new reagent lot
Auto-QC User-defined time interval
View Calibration Graphical display of calibration curves
QC Data Graphical display of QC plot (histogram or Levey-Jennings) with Westgard Rules; RealTime QC; QCC PowerPak™ efficiency package
User Interface/Data Management
Monitor 17-inch diagonal touchscreen with adjustable height
Operating Computer Linux, 1 GB RAM
System Documentation Operator manual
Data Storage 100,000 patient tests (10 MB), 100,000 QC results (10 MB), 9000 calibrations (5 yrs, 18 MB)
Auto-System Check User-defined time of day
Host Interface RS 232C bidirectional
Host Query System requests work order or batch of work orders from host
Remote Access and Service Ethernet port for remote access via Siemens Remote Service (starting with software version 10.1); modem for remote diagnostic access
Removable Media
Removable Media CD, DVD, and USB (starting with software version 10.0)
General Specifications
Power Requirements System 115 VAC at 60 Hz (nominal); 11 amps max; 1.3 kW consumption in operating state 230 VAC at 50 Hz (nominal); 5.5 amps max; 1.3 kW consumption in operating state
Water Requirements1
  • Instrument feed pressurized water source
  • <3.8 bar (<55 psi)
  • Instrument feed water system must maintain
  • stable DO2 content between 5 and 8 ppm²
  • Temperature: <35°C (<95°F)
  • Resistivity: >10 megohms cm
  • Bacterial content: <10 colony forming units/mL
  • System feed water line must not exceed 3 m (12 feet)
Water System
  • Instrument may be supplied with a water purifier that provides instrument feed water
  • If an alternative water system is used, water must adhere to Siemens water specifications
Maximum Water Consumption 5.0 L/hr (1.32 gal/hr)
Drain Requirements 40 L/hr (10.6 gal/hr)
Dimensions Normal operation: 187 cm W x 122 cm H x 132 cm D (74 in W x 48 in H x 52 in D) With monitor fully extended, lids fully open, and external UPS: 190 cm W x 191 cm H x 155 cm D (75 in. W x 75 in. H x 61 in. D)
Weight 349 kg (770 lb)
Compliance Complies with international environmental, health, and safety standards
Noise Specifications <75 dBA at 1 m while operating
Average Heat Output 1,100 W/hr (3753 BTU/hr)
Operating Temperature Range 18–30ºC (64–86ºF)
Ambient Humidity 20–80% (noncondensing)
Anemia/Iron Metabolism Ferritin Folatea Vitamin B12a Bone Metabolism Vitamin D Total4,a Cardiac BNP2a CKMB Mass CKMB Isoenzyme CardioPhase® High-sensitivity CRP High-sensitivity troponin I (TNIH)1,a Myoglobin NT-proBNPa Troponin Ia Diabetes Hemoglobin A1cb Microalbumin Drugs of Abuse/Toxicology 6-Acetylmorphine (6-AM)3 Acetaminophen Amphetamines Barbiturates Barbiturates (Serum)3 Benzodiazepines Benzodiazepines (Serum)3 Caffeine3 Cannabinoids (THC) Cocaine Metabolite Ecstasy Ethyl Alcohol Methadone Methaqualone3 Opiates Phencyclidine Propoxyphene3 Salicylate Tricyclic Antidepressants3 General Chemistry Acid Phosphatase Alanine Aminotransferase (ALT) Albumin (BCP) Alkaline Phosphatase (ALP) Ammonia Amylase Aspartate Aminotransferase Bilirubin, Direct Bilirubin, Total Calcium (CPC) Carbon Dioxide, Enzymatic Chloride Cholesterol Cholinesterase Creatinine Creatinine, Enzymatic Creatine Kinase Dibucaine Number4,c Gamma Glutamyltransferase (GGT) Glucose HDL Cholesterol Hemolyzed Glucose4,c Iron Lactate Lactate Dehydrogenase LDL Cholesterol Lipase Magnesium Phosphorus Potassium Sodium Total Iron Binding Capacity Total Protein Total Protein (CSF/Urine) Triglycerides Urea Nitrogen (BUN) Uric Acid Immunosuppressant Drugs Cyclosporineb Cyclosporine, Extended Rangeb Mycophenolic Acid Sirolimusb Tacrolimusb Oncology Free PSA Total PSA   Reproductive Endocrinology hCG Specific Proteins Complement C3 Complement C4 CRP CRP, Extended Range Immunoglobulin A Immunoglobulin G Immunoglobulin M Prealbumin Transferrin Therapeutic Drug Monitoring (TDM) Amikacin3 Carbamazepine Digitoxin Digoxin Gabepentinc,d Gentamicin Lamotriginec,d Levetiracetamc,d Lidocaine Lithium Methotrexate3 N-Acetylprocainamide (NAPA) Phenobarbital Phenytoin Procainamide Theophylline Tobramycin Topiramatec,d Valproic Acid Vancomycin Zonisamidec,d Thyroid Free T3a Free T4a T Uptake Total T4 TSHa