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ADVIA 1800 Chemistry System

ADVIA 1800 Chemistry System

Brand: Siemens


The ADVIA® 1800 Clinical Chemistry System pushes the limit of productivity. Its extensive menu allows integration of testing for clinical chemistry, drugs-of-abuse, therapeutic drug monitoring (TDM) and specific proteins like Cystatin C and CardioPhase® hsCRP. The ADVIA 1800 Clinical Chemistry System offers:

Product Details

The ADVIA 1800® Clinical Chemistry System pushes the limit of productivity of the core lab and meets the turnaround-time (TAT) goals of today’s laboratories. Its extensive and growing menu allows integration of general clinical chemistry testing with testing for drugs-of-abuse, therapeutic drug monitoring (TDM), special chemistry and specific proteins like Cystatin C and CardioPhase® hsCRP.
The ADVIA 1800 Clinical Chemistry System is an ideal solution for mid- to high-volume chemistry analysis. Featuring intuitive new software and capabilities, it’s designed to deliver power and speed to meet the most demanding performance needs. The ADVIA 1800 System moves laboratories to smarter chemistry testing.   Automation ready design
  • Point-in-space aspiration offers connectivity to a track, VersaCell or rack handler without robotics or special hardware
  • Redundant sample loading for built-in backup and easy handling of non-routine samples
  • Direct sampling from track prevents detaining tubes at analyzer and reduces aliquoting
Peak productivity
  • Throughput of up to 1,800 tests per hour provides the speed to keep pace with workload peaks
  • 200 Basic metabolic panels per hour to meet turnaround-time demands
  • Automatic Sample Retain technology provides the ability to perform reruns and dilutions without the need to retrieve primary tubes
  • Consolidation power with a comprehensive menu, consistent cycle times, speed and open application capability
Total system reliability
  • Minimal-maintenance ISEs
  • Robust hardware and simplified software design, with automatic calibration validation and tracking
  • Advances in reagent onboard stability, calibration frequency, interference reduction and assay linearity expansion
  • Direct water connection
  • Remote diagnostics and ILQC (Inter-Laboratory Quality Control) options
Easy efficiency
  • Large onboard reagent capacity and optional concentrated reagents reduce interruptions
  • High-resolution touchscreen delivers push-button operation
  • Reagent pause capability and onboard Sample Pause button make loading easy
  • Minimal maintenance requirements, including no-maintenance oil bath
  • Sample integrity checking, including serum indices reporting, short sample flagging and clot detection, reduces manual intervention
Type of System Random, continuous access, batch, discrete processing
Throughput Rate Up to 1800 tests/hour: 1200 tests/hour colorimetric, 600 tests/hour ISE
Assay Capacity Onboard 55 including 3 ISE
Sample Handling
Sample Tubes 5 mL, 7 mL, 10 mL tubes, 2 mL sample cups
Sample Tray 84 samples, positive sample identification
Sample Rack Handler (optional) Universal 5-position rack, 425 total onboard capacity, continuous feed capability
Sample Integrity Check Qualitative check for hemolysis, lipemia, and icterus
STAT Sample Loading 84, not dedicated
Bar Codes Interleaved 2 of 5, Code 39, Code 128, Codabar (NW7)
Auto-repeat Automatic repeat testing from the retained prediluted sample or original sample
Auto-dilution Automatic dilution from retained prediluted sample
Auto-reflex Testing Automatic ability to perform 3 additional tests based on results of first test
Primary Probe Liquid Level Sensing, Crash Protection, Clot/Clog Detection, Short Sample Detection
Microvolume Technology
Automatic Sample Predilution Samples diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests), retained for auto-repeat until results are available
Predilution Tray 120 dilution cuvettes
Original Sample Volume 2 to 30 μL; average of 2-3 μL per test
Average Reagent Volume 80-120 μL per test
Storage Capacity Onboard 25,200 tests average; Usage of concentrated reagents increases maximum capacity
Reaction Area
Reaction Tray 221 reusable plastic cuvettes
Cuvette Optical Path Length 10 mm
Reaction Bath Inert fluorocarbon oil circulation system, 37°C
Photometer 14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm)
Light Source 12 V, 50 W halogen lamp, cooled by forced water circulation
Assay Methods Endpoint, rate reaction, 2-point rate, multipoint homogeneous immunoassay
Reaction Times 3, 4, 5, 10, 15, and 21 minutes
Automatic Correction Serum blank, cell blank, measurement point change, sample volume change in reassay
Point Forwarding Automatically extends linearity over assay range samples
Reagent Handling
Reagent Tray 2 trays, 56 positions each, refrigerated
Reagent Capacity Onboard 52 colorimetric methods
Dispensing System 2 probes with Liquid Level Sensing and Liquid Surface Verification
Reagent Wedges 20, 40, 70 mL bar-code-labeled wedges
Reagent Inventory Management Tracks tests remaining, lot number, onboard stability, and expiration date
Reagent Dilutions Capability to dilute concentrated reagents onboard
Onboard Stability Up to 60 days
Open System Capability
Channels 200 channels, includes user-defined applications
3rd Party Applications Varies by country, can be configured on system
ISE Indirect simultaneous measurement of Na+, K+, Cl -
Sample Volume 22 μL for all three tests
Priming Automatic priming cycle
Electrode Shelf Life 30,000 samples or 3 months
Throughput Rate 600 tests/hour; 200 tubes/hour
Calibration Interval Up to 60 days, tracked by software
Auto-calibration/Auto-QC User-defined time interval or with new reagent container
View Calibration/QC Data Graphical display of calibration curves and QC; Siemens Remote Service QC monitoring
Calibration/Control Tray 61 refrigerated positions for calibrators, controls, and diluents
Data Management
Operating Computer Windows® XP, 1 GB RAM, touch screen monitor 19”
System Documentation Operator manual and assay sheets online
Host Interface RS 232C bidirectional
Data Storage 70,000 patient tests
Onboard Maintenance Logs Schedule and monitor routine maintenance activities via software
Host Query ASCII; system requests work order or batch of work orders from host
General Specifications
Power Requirements 200/220/230/240 V +/– 10%, 20 A, 50/60 Hz, 3 KVA
Water Requirements Deionized water from pressurized water (10-30 psi/169-207 KPa) Average Consumption: 30 liters per hour
Drain Requirements Minimum of 40 liters per hour
Dimensions ADVIA 1800: 44.6 (h) x 58.3 (w) x 34.5 (d) in, 113.3 (h) x 148.0 (w) x 87.6 (d) cm Universal Rack Handler: 37 (h) x 29 (w) x 41 (d) in, 86.4 (h) x 73.7 (w) x 104.1 (d) cm
Weight ADVIA 1800: 1,323 lbs (600 kg) Universal Rack Handler: 178 lbs (81 kg)
Compliance UL, cUL, CE
Noise Specifications Open cover less than 70 db
Average Heat Output 4,299 BTU/hour @ 50 Hz, 3,023 BTU/hour @ 60 Hz
Operating Temperature Range 18°-30°C/64°-86°F
Ambient Humidity 40%-70%
  • Hemoglobin A1c
  • Microalbumin
  Drugs of Abuse/Toxicology
  • 6-Acetylmorphinea (6-AM)
  • Acetaminophen
  • Amphetamines
  • Barbiturates
  • Barbiturates, Serum
  • Benzodiazepines
  • Benzodiazepines, Serum
  • Cannabinoids (THC)
  • Cocaine Metabolite
  • Ecstasy
  • Ethanol
  • Methadone
  • Methadone Metabolites, EDDP
  • Opiates
  • Phencyclidine
  • Propoxyphene
  • Salicylate
  • Validity Test
  • Tricyclic Antidepressants
  General Chemistry
  • Alanine Aminotransferaseb
  • Alanine Aminotransferase (P5P)b
  • Albumin (BCG)c
  • Albumin (BCP)
  • Alkaline Phosphatase (AMP)c
  • Alkaline Phosphatase (DEA)1
  • Ammonia
  • Amylase
  • Aspartate Aminotransferaseb
  • Aspartate Aminotransferase (P5P)b
  • Bilirubin, Direct
  • Bilirubin, Total
  • Calcium (Arsenazo)b
  • Calcium (CPC)b
  • Carbon Dioxide, Enzymaticb
  • Chloride (ISE)
  • Cholesterolb
  • Cholinesterase
  • Creatine Kinase
  • Creatinineb
  • Creatinine, Enzymatic
  • Fructosamine
  • Gamma-Glutamyltransferase (GGT)
  • Glucose (Hexokinase)b
  • Glucose (Oxidase)b
  • HDL Cholesterol
  • Iron
General Chemistry (cont.)
  • Lactate
  • Lactate Dehydrogenase (L-P)
  • Lactate Dehydrogenase (P-L)
  • LDL Cholesterol
  • Lipase
  • Magnesiumb
  • Pancreatic Amylase
  • Phosphorusb
  • Potassium
  • Sodium
  • Total Iron Binding Capacity (TIBC)
  • Total Proteinb
  • Total Protein (CSF/Urine)
  • Triglyceridesb
  • Urea Nitrogen (BUN)b
  • Uric Acidb
  Specific Proteins
  • α1-Acid Glycoprotein
  • α1-Antitrypsin
  • Antistreptolysin O
  • Apolipoprotein A1
  • Apolipoprotein B
  • β2 Microglobulin
  • CardioPhase® hsCRP
  • Complement C3
  • Complement C4
  • CRP
  • CRP, Wide Range
  • Cystatin C
  • Ferritin
  • Haptoglobin
  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M
  • Lipoprotein(a)
  • Myoglobin
  • Prealbumin
  • Rheumatoid Factor
  • Transferrin
Therapeutic Drug Monitoring (TDM)
  • Carbamazepine
  • Digoxin
  • Gentamicin
  • Lithium
  • Phenobarbital
  • Phenytoin
  • Theophylline
  • Tobramycin
  • Valproic Acid
  • Vancomycin
  Validity Testing
  • Creatinine Specimend
  • Nitrite Specimend
  • Oxidant Specimend
  • pH Specimend
  • Specific Gravity Specimend